The 10,000 Brains Project accelerates the use of computational approaches such as AI in the fight against FTD and other neurodegenerative disorders. The organization’s first major initiative is the creation of a digital brain bank. Neuropathology is considered the gold standard for disease understanding, but most brain tissue is stored away on glass slides. This project will generate ultra-high resolution whole slide images from up to 10,000 patients’ brain tissue samples. The dataset will be shared freely with the global research community, where it can be used to supercharge the pursuit of novel biomarkers and more personalized treatments.